Protective Effect of Heme Oxygenase-1 on High Glucose-Induced Pancreatic β-Cell Injury
BackgroundGlucose toxicity that is caused by chronic exposure to a high glucose concentration leads to islet dysfunction and induces apoptosis in pancreatic β-cells. Heme oxygenase-1 (HO-1) has been identified as an anti-apoptotic and cytoprotective gene. The purpose of this study is to investigate...
Main Authors: | Eun-Mi Lee, Young-Eun Lee, Esder Lee, Gyeong Ryul Ryu, Seung-Hyun Ko, Sung-Dae Moon, Ki-Ho Song, Yu-Bae Ahn |
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Format: | Article |
Language: | English |
Published: |
Korean Diabetes Association
2011-10-01
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Series: | Diabetes & Metabolism Journal |
Subjects: | |
Online Access: | http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-35-469.pdf |
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