Towards Lipidomics of Low-Abundant Species for Exploring Tumor Heterogeneity Guided by High-Resolution Mass Spectrometry Imaging

Towards Lipidomics of Low-Abundant Species for Exploring Tumor Heterogeneity Guided by High-Resolution Mass Spectrometry Imaging

Many studies have evidenced the main role of lipids in physiological and also pathological processes such as cancer, diabetes or neurodegenerative diseases. The identification and the in situ localization of specific low-abundant lipid species involved in cancer biology are still challenging for bot...

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Bibliographic Details
Main Authors: Jonathan Cimino, David Calligaris, Johann Far, Delphine Debois, Silvia Blacher, Nor Eddine Sounni, Agnès Noel, Edwin De Pauw
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:International Journal of Molecular Sciences
Subjects:
MALDI mass spectrometry imaging
FTICR mass spectrometry
lipidomics
hypoxia
necrosis
cancer
Online Access:http://www.mdpi.com/1422-0067/14/12/24560

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