Comprehensive study on transglycosylation of CGTase from various sources
Transglycosylation is the in-vivo or in-vitro process of transferring glycosyl groups from a donor to an acceptor, which is usually performed by enzymatic reactions because of their simplicity, low steric hindrance, high region-specificity, low production cost, and mild processing conditions. One of...
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doaj-bc1cb95362704506bbb85a0973a899012021-03-03T04:24:56ZengElsevierHeliyon2405-84402021-02-0172e06305Comprehensive study on transglycosylation of CGTase from various sourcesChin Hui Lim0Babak Rasti1Joko Sulistyo2Mansoor Abdul Hamid3Faculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, MalaysiaFaculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, Malaysia; Corresponding author.Faculty of Biotechnology, University of Surabaya, Jalan Ngagel Jaya Selatan, Surabaya, 60294, IndonesiaFaculty of Food Science and Nutrition, Universiti Malaysia Sabah, Jalan UMS, 88400, Kota Kinabalu, Sabah, MalaysiaTransglycosylation is the in-vivo or in-vitro process of transferring glycosyl groups from a donor to an acceptor, which is usually performed by enzymatic reactions because of their simplicity, low steric hindrance, high region-specificity, low production cost, and mild processing conditions. One of the enzymes commonly used in the transglycosylation reaction is cyclodextrin glucanotransferase (CGTase). The transglycosylated products, catalyzed by CGTase, are widely used in food additives, supplements, and personal care and cosmetic products. This is due to improvements in the solubility, stability, bioactivity and length of the synthesized products. This paper's focus is on the importance of enzymes used in the transglycosylation reaction, their characteristics and mechanism of action, sources and production yield, and donor and acceptor specificities. Moreover, the influence of intrinsic and extrinsic factors on the enzymatic reaction, catalysis of glycosidic linkages, and advantages of CGTase transglycosylation reactions are discussed in detail.http://www.sciencedirect.com/science/article/pii/S2405844021004102Transglycosylation reactionCyclodextrin glucanotransferaseCGTase |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Chin Hui Lim Babak Rasti Joko Sulistyo Mansoor Abdul Hamid |
spellingShingle |
Chin Hui Lim Babak Rasti Joko Sulistyo Mansoor Abdul Hamid Comprehensive study on transglycosylation of CGTase from various sources Heliyon Transglycosylation reaction Cyclodextrin glucanotransferase CGTase |
author_facet |
Chin Hui Lim Babak Rasti Joko Sulistyo Mansoor Abdul Hamid |
author_sort |
Chin Hui Lim |
title |
Comprehensive study on transglycosylation of CGTase from various sources |
title_short |
Comprehensive study on transglycosylation of CGTase from various sources |
title_full |
Comprehensive study on transglycosylation of CGTase from various sources |
title_fullStr |
Comprehensive study on transglycosylation of CGTase from various sources |
title_full_unstemmed |
Comprehensive study on transglycosylation of CGTase from various sources |
title_sort |
comprehensive study on transglycosylation of cgtase from various sources |
publisher |
Elsevier |
series |
Heliyon |
issn |
2405-8440 |
publishDate |
2021-02-01 |
description |
Transglycosylation is the in-vivo or in-vitro process of transferring glycosyl groups from a donor to an acceptor, which is usually performed by enzymatic reactions because of their simplicity, low steric hindrance, high region-specificity, low production cost, and mild processing conditions. One of the enzymes commonly used in the transglycosylation reaction is cyclodextrin glucanotransferase (CGTase). The transglycosylated products, catalyzed by CGTase, are widely used in food additives, supplements, and personal care and cosmetic products. This is due to improvements in the solubility, stability, bioactivity and length of the synthesized products. This paper's focus is on the importance of enzymes used in the transglycosylation reaction, their characteristics and mechanism of action, sources and production yield, and donor and acceptor specificities. Moreover, the influence of intrinsic and extrinsic factors on the enzymatic reaction, catalysis of glycosidic linkages, and advantages of CGTase transglycosylation reactions are discussed in detail. |
topic |
Transglycosylation reaction Cyclodextrin glucanotransferase CGTase |
url |
http://www.sciencedirect.com/science/article/pii/S2405844021004102 |
work_keys_str_mv |
AT chinhuilim comprehensivestudyontransglycosylationofcgtasefromvarioussources AT babakrasti comprehensivestudyontransglycosylationofcgtasefromvarioussources AT jokosulistyo comprehensivestudyontransglycosylationofcgtasefromvarioussources AT mansoorabdulhamid comprehensivestudyontransglycosylationofcgtasefromvarioussources |
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