Predictors of perioperative morbidity and mortality in adult living donor liver transplantations: report of results of a tertiary hospital

• Main Authors: Burcu Hizarci, Pelin Karaaslan, Gokhan Ertugrul, Mesut Yilmaz, Yavuz Demiraran, Huseyin Oz
• Format: Article
• Language: English
• Published: SpringerOpen 2020-11-01
• Series: Ain Shams Journal of Anesthesiology
• Subjects: Liver; Living donor transplantation; Mortality
• Online Access: http://link.springer.com/article/10.1186/s42077-020-00094-7

Abstract Background The aim of this study was to investigate the risk factors effective in perioperative morbidity and mortality in 161 living donor liver transplantations (LDLT). Results The most common indication for living donor transplantation was cryptogenic cirrhosis. The most common complication was biliary problems in 62.16% cases. Sepsis was the most common cause of in 52%. Patients in whom sepsis was observed, significantly prolonged stay under mechanical ventilation and prolonged ICU stay were detected. In patient group in whom mortality was observed, higher amounts of erythrocytes, fresh frozen plasma (FFP), and platelets were transfused, and patients remained longer under mechanical ventilation treatment, and in the ICU. Conclusion Perioperative morbidity and mortality was found to be significantly related with higher amounts of erythrocytes and FFP transfusions and longer operative and warm ischemia times. Sepsis was found to be the most common cause of mortality.