Porphyromonas gingivalis lipopolysaccharide induces cognitive dysfunction, mediated by neuronal inflammation via activation of the TLR4 signaling pathway in C57BL/6 mice

Porphyromonas gingivalis lipopolysaccharide induces cognitive dysfunction, mediated by neuronal inflammation via activation of the TLR4 signaling pathway in C57BL/6 mice

Abstract Background Porphyromonas gingivalis lipopolysaccharide (P. gingivalis-LPS) is one of the major pathogenic factors of chronic periodontitis (CP). Few reports on the correlation between P. gingivalis-LPS and cognitive function exist. Thus, the present study aimed to investigate the effects of...

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Bibliographic Details
Main Authors: Jing Zhang, Chunbo Yu, Xuan Zhang, Huiwen Chen, Jiachen Dong, Weili Lu, Zhongchen Song, Wei Zhou
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Journal of Neuroinflammation
Subjects:
Porphyromonas gingivalis
Lipopolysaccharide
Cognition
Neuroinflammation
TLR4
Online Access:http://link.springer.com/article/10.1186/s12974-017-1052-x

Internet

http://link.springer.com/article/10.1186/s12974-017-1052-x

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