Disruption of the GluR2/GAPDH complex protects against ischemia-induced neuronal damage
Background: Excitotoxicity and neuronal death following ischemia involve AMPA (α-amino-3hydroxy-5-methylisoxazole-4-propionic acid) glutamate receptors. We have recently reported that the GluR2 subunit of AMPA receptors (AMPARs) forms a protein complex with GAPDH (glyceraldehyde-3-phosphate dehydrog...
Main Authors: | Dongxu Zhai, Shupeng Li, Min Wang, Kyle Chin, Fang Liu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-06-01
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Series: | Neurobiology of Disease |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996113000375 |
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