Syntheses of Stable Isotope Labeled D12-Malachite Green
The efficient synthesis of stable isotope labeled D12-Malachite Green with CD3OD as the precursor by methylation, condensation and oxidation was presented. The yields of D12-Malachite Green was 50.1 % based on CD3OD consumed. The product was ideatified by HPLC, MS, and NMR to be the target compound...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Board of Journal of Isotopes
2014-02-01
|
| Series: | Journal of Isotopes |
| Subjects: | |
| Online Access: | http://www.tws.org.cn/CN/10.7538/tws.2014.27.02.0077 |
| Summary: | The efficient synthesis of stable isotope labeled D12-Malachite Green with CD3OD as the precursor by methylation, condensation and oxidation was presented. The yields of D12-Malachite Green was 50.1 % based on CD3OD consumed. The product was ideatified by HPLC, MS, and NMR to be the target compound. Its chemical purity and isotopic enrichment were higher than 99.0 atom%D. The result showed that the D12-Malachite Green could be used as internal standard in the field of food safety.
|
|---|---|
| ISSN: | 1000-7512 1000-7512 |