Eosinophilic esophagitis

Abstract Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last 15 years. Diagnosis of the disorder is dependent on the patient’s clinical manifestations, and must be confirmed by histologic findings on esophageal mucosal biopsies...

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Main Authors: Stuart Carr, Edmond S. Chan, Wade Watson
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Allergy, Asthma & Clinical Immunology
Online Access:http://link.springer.com/article/10.1186/s13223-018-0287-0
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spelling doaj-bc499fc7c09544769200bc74b99968f72020-11-25T01:38:31ZengBMCAllergy, Asthma & Clinical Immunology1710-14922018-09-0114S211110.1186/s13223-018-0287-0Eosinophilic esophagitisStuart Carr0Edmond S. Chan1Wade Watson2Department of Pediatrics, University of AlbertaDivision of Allergy & Immunology, Department of Pediatrics, University of British ColumbiaDivision of Allergy, Department of Pediatrics, IWK Health Centre, Dalhousie UniversityAbstract Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last 15 years. Diagnosis of the disorder is dependent on the patient’s clinical manifestations, and must be confirmed by histologic findings on esophageal mucosal biopsies. Patients with EoE should be referred to an allergist for optimal management, which may include dietary modifications and pharmacologic agents such as corticosteroids, and for the diagnosis and management of comorbid atopic conditions. Mechanical dilation of the esophagus may also be necessary. The epidemiology, pathophysiology, diagnosis, treatment, and prognosis of EoE are discussed in this review.http://link.springer.com/article/10.1186/s13223-018-0287-0
collection DOAJ
language English
format Article
sources DOAJ
author Stuart Carr
Edmond S. Chan
Wade Watson
spellingShingle Stuart Carr
Edmond S. Chan
Wade Watson
Eosinophilic esophagitis
Allergy, Asthma & Clinical Immunology
author_facet Stuart Carr
Edmond S. Chan
Wade Watson
author_sort Stuart Carr
title Eosinophilic esophagitis
title_short Eosinophilic esophagitis
title_full Eosinophilic esophagitis
title_fullStr Eosinophilic esophagitis
title_full_unstemmed Eosinophilic esophagitis
title_sort eosinophilic esophagitis
publisher BMC
series Allergy, Asthma & Clinical Immunology
issn 1710-1492
publishDate 2018-09-01
description Abstract Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last 15 years. Diagnosis of the disorder is dependent on the patient’s clinical manifestations, and must be confirmed by histologic findings on esophageal mucosal biopsies. Patients with EoE should be referred to an allergist for optimal management, which may include dietary modifications and pharmacologic agents such as corticosteroids, and for the diagnosis and management of comorbid atopic conditions. Mechanical dilation of the esophagus may also be necessary. The epidemiology, pathophysiology, diagnosis, treatment, and prognosis of EoE are discussed in this review.
url http://link.springer.com/article/10.1186/s13223-018-0287-0
work_keys_str_mv AT stuartcarr eosinophilicesophagitis
AT edmondschan eosinophilicesophagitis
AT wadewatson eosinophilicesophagitis
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