Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia
Vascular endothelial growth factor-A (VEGF-A) is best known as a key regulator of the formation of new blood vessels. Neutralization of VEGF-A with anti-VEGF therapy e.g. bevacizumab, can be painful, and this is hypothesized to result from a loss of VEGF-A-mediated neuroprotection. The multiple vegf...
Main Authors: | R.P. Hulse, N. Beazley-Long, J. Hua, H. Kennedy, J. Prager, H. Bevan, Y. Qiu, E.S. Fernandes, M.V. Gammons, K. Ballmer-Hofer, A.C. Gittenberger de Groot, A.J. Churchill, S.J. Harper, S.D. Brain, D.O. Bates, L.F. Donaldson |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-11-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996114002435 |
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