A Case of Gingival Metastasis from Rectal Cancer in Which Immunohistochemistry and PET-CT Were Useful for the Diagnostic Procedure

A 50-year-old man was referred to our hospital because of a 2-month history of painful gingival swelling. Histopathological examination of the biopsy specimen showed a metastatic adenocarcinoma, and a chest-abdominopelvic CT showed multiple metastases in the lung, liver, and spleen, but failed to de...

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Main Authors: Masami Yamauchi, Katsunori Shinozaki, Mihoko Doi, Tomoko Nitta, Takashi Nishisaka
Format: Article
Language:English
Published: Karger Publishers 2014-03-01
Series:Case Reports in Oncology
Subjects:
Online Access:http://www.karger.com/Article/FullText/362185
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spelling doaj-bc5a4af43ad4436886a2ed2fdf11943b2020-11-24T21:45:03ZengKarger PublishersCase Reports in Oncology1662-65752014-03-017124625110.1159/000362185362185A Case of Gingival Metastasis from Rectal Cancer in Which Immunohistochemistry and PET-CT Were Useful for the Diagnostic ProcedureMasami YamauchiKatsunori ShinozakiMihoko DoiTomoko NittaTakashi NishisakaA 50-year-old man was referred to our hospital because of a 2-month history of painful gingival swelling. Histopathological examination of the biopsy specimen showed a metastatic adenocarcinoma, and a chest-abdominopelvic CT showed multiple metastases in the lung, liver, and spleen, but failed to demonstrate the primary tumor. He had never complained of abdominal symptoms, and physical examination did not show any abnormality in the abdomen. However, immunohistochemical staining including caudal-related homeobox transcription factor (CDX-2) of the gingival tumor and PET-CT findings strongly suggested colorectal cancer as the origin. Colonoscopy then revealed a tumor in the rectum, and systemic chemotherapy was started immediately.http://www.karger.com/Article/FullText/362185PET-CTColorectal cancerImmunohistochemistryGingival metastasis
collection DOAJ
language English
format Article
sources DOAJ
author Masami Yamauchi
Katsunori Shinozaki
Mihoko Doi
Tomoko Nitta
Takashi Nishisaka
spellingShingle Masami Yamauchi
Katsunori Shinozaki
Mihoko Doi
Tomoko Nitta
Takashi Nishisaka
A Case of Gingival Metastasis from Rectal Cancer in Which Immunohistochemistry and PET-CT Were Useful for the Diagnostic Procedure
Case Reports in Oncology
PET-CT
Colorectal cancer
Immunohistochemistry
Gingival metastasis
author_facet Masami Yamauchi
Katsunori Shinozaki
Mihoko Doi
Tomoko Nitta
Takashi Nishisaka
author_sort Masami Yamauchi
title A Case of Gingival Metastasis from Rectal Cancer in Which Immunohistochemistry and PET-CT Were Useful for the Diagnostic Procedure
title_short A Case of Gingival Metastasis from Rectal Cancer in Which Immunohistochemistry and PET-CT Were Useful for the Diagnostic Procedure
title_full A Case of Gingival Metastasis from Rectal Cancer in Which Immunohistochemistry and PET-CT Were Useful for the Diagnostic Procedure
title_fullStr A Case of Gingival Metastasis from Rectal Cancer in Which Immunohistochemistry and PET-CT Were Useful for the Diagnostic Procedure
title_full_unstemmed A Case of Gingival Metastasis from Rectal Cancer in Which Immunohistochemistry and PET-CT Were Useful for the Diagnostic Procedure
title_sort case of gingival metastasis from rectal cancer in which immunohistochemistry and pet-ct were useful for the diagnostic procedure
publisher Karger Publishers
series Case Reports in Oncology
issn 1662-6575
publishDate 2014-03-01
description A 50-year-old man was referred to our hospital because of a 2-month history of painful gingival swelling. Histopathological examination of the biopsy specimen showed a metastatic adenocarcinoma, and a chest-abdominopelvic CT showed multiple metastases in the lung, liver, and spleen, but failed to demonstrate the primary tumor. He had never complained of abdominal symptoms, and physical examination did not show any abnormality in the abdomen. However, immunohistochemical staining including caudal-related homeobox transcription factor (CDX-2) of the gingival tumor and PET-CT findings strongly suggested colorectal cancer as the origin. Colonoscopy then revealed a tumor in the rectum, and systemic chemotherapy was started immediately.
topic PET-CT
Colorectal cancer
Immunohistochemistry
Gingival metastasis
url http://www.karger.com/Article/FullText/362185
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