Optimization of Collagen Chemical Crosslinking to Restore Biocompatibility of Tissue-Engineered Scaffolds
Collagen scaffolds, one of the most used biomaterials in corneal tissue engineering, are frequently crosslinked to improve mechanical properties, enzyme tolerance, and thermal stability. Crosslinkers such as 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) are compatible with tissu...
Main Authors: | Mohammad Mirazul Islam, Dina B. AbuSamra, Alexandru Chivu, Pablo Argüeso, Claes H. Dohlman, Hirak K. Patra, James Chodosh, Miguel González-Andrades |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-06-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/13/6/832 |
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