Protective effects of Cinnamomum zeylanicum L. (Darchini) in acetaminophen-induced oxidative stress, hepatotoxicity and nephrotoxicity in mouse model

Protective effects of Cinnamomum zeylanicum L. (Darchini) in acetaminophen-induced oxidative stress, hepatotoxicity and nephrotoxicity in mouse model

Cinnamomum zeylanicum, a widely used spice and flavor, is used in the treatment and prevention of many diseases. In the current study, Balb/c mice were pretreated with cinnamon bark aqueous extract (200 mg/kg/day i.g.) 14 days prior to intragastrically administer single toxic dose of acetaminophen (...

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Bibliographic Details
Main Authors: Zulfia Hussain, Junaid Ali Khan, Arfa Arshad, Palwasha Asif, Haroon Rashid, Muhammad Imran Arshad
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Cinnamon
Acetaminophen
Acute liver injury
Nephrotoxicity
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332218356245

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