Drugs Commonly Applied to Kidney Patients May Compromise Renal Tubular Uremic Toxins Excretion
In chronic kidney disease (CKD), the secretion of uremic toxins is compromised leading to their accumulation in blood, which contributes to uremic complications, in particular cardiovascular disease. Organic anion transporters (OATs) are involved in the tubular secretion of protein-bound uremic toxi...
Main Authors: | Silvia M. Mihaila, João Faria, Maurice F. J. Stefens, Dimitrios Stamatialis, Marianne C. Verhaar, Karin G. F. Gerritsen, Rosalinde Masereeuw |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-06-01
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Series: | Toxins |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6651/12/6/391 |
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