Long-term potentiation of high-frequency oscillation and synaptic transmission characterize in vitro NMDA receptor-dependent epileptogenesis in the hippocampus

Long-term potentiation of high-frequency oscillation and synaptic transmission characterize in vitro NMDA receptor-dependent epileptogenesis in the hippocampus

The implication of high-frequency network oscillations (HFOs) in brain pathology resides in as yet unclear mechanisms. Employing field recordings from ventral hippocampal slices and two models of epileptogenesis (i.e. establishment of interictal-like persistent bursts), we found that HFOs associated...

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Bibliographic Details
Main Authors: Christos Moschovos, George Kostopoulos, Costas Papatheodoropoulos
Format: Article
Language:English
Published: Elsevier 2008-02-01
Series:Neurobiology of Disease
Subjects:
Synaptic transmission
High-frequency oscillation
Fast ripples
Epileptogenesis
Persistent interictal burst
CA3
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107002252

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