Multi-Loop Model of Alzheimer Disease: An Integrated Perspective on the Wnt/GSK3β, α-Synuclein, and Type 3 Diabetes Hypotheses
As the prevalence of Alzheimer disease (AD) continues to rise unabated, new models have been put forth to improve our understanding of this devastating condition. Although individual models may have their merits, integrated models may prove more valuable. Indeed, the reliable failures of monotherapi...
Main Authors: | Nicholas G. Norwitz, Adrian Soto Mota, Sam G. Norwitz, Kieran Clarke |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2019-07-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/article/10.3389/fnagi.2019.00184/full |
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