Multi-Loop Model of Alzheimer Disease: An Integrated Perspective on the Wnt/GSK3β, α-Synuclein, and Type 3 Diabetes Hypotheses

As the prevalence of Alzheimer disease (AD) continues to rise unabated, new models have been put forth to improve our understanding of this devastating condition. Although individual models may have their merits, integrated models may prove more valuable. Indeed, the reliable failures of monotherapi...

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Bibliographic Details
Main Authors: Nicholas G. Norwitz, Adrian Soto Mota, Sam G. Norwitz, Kieran Clarke
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Aging Neuroscience
Subjects:
tau
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00184/full

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