Degradable Dextran Nanopolymer as a Carrier for Choline Kinase (ChoK) siRNA Cancer Therapy

Although small interfering RNA (siRNA) therapy has proven to be a specific and effective treatment in cells, the delivery of siRNA is a challenge for the applications of siRNA therapy. We present a degradable dextran with amine groups as an siRNA nano-carrier. In our nano-carrier, the amine groups a...

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Bibliographic Details
Main Authors: Zhihang Chen, Balaji Krishnamachary, Zaver M. Bhujwalla
Format: Article
Language:English
Published: MDPI AG 2016-02-01
Series:Nanomaterials
Subjects:
Online Access:http://www.mdpi.com/2079-4991/6/2/34