Catalysis in the alkylation reaction of 1-naphthol with epichlorohydrin

Catalysis in the alkylation reaction of 1-naphthol with epichlorohydrin

Two new and improved procedures were developed for the synthesis of 1-(1-naphthyloxy)-2,3-epoxypropane as an important intermediate in the production of the beta-blocker and antioxidant 1-[(1-methylethyl)amino]-3-(1-naphthyloxy)- 2-propanol (propranolol). Both base homogeneous and heterogeneous PTC...

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Bibliographic Details
Main Authors: Jovanović Slobodanka, Vico-Stevanović Milanka, Uglješić-Kilibarda Dragana, Popadić Dragica, Simić Slobodanka, Dželetović Dijamanda
Format: Article
Language:English
Published: Serbian Chemical Society 2006-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
heterogeneous ptc catalysis
base homogeneous catalysis
selectivity
yield
model system
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2006/0352-51390609867J.pdf

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