Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans

Synthetic Ligands of Cannabinoid Receptors Affect Dauer Formation in the Nematode Caenorhabditis elegans

Under adverse environmental conditions the nematode Caenorhabditis elegans can enter an alternate developmental stage called the dauer larva. To identify lipophilic signaling molecules that influence this process, we screened a library of bioactive lipids and found that AM251, an antagonist of the h...

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Bibliographic Details
Main Authors: Pedro Reis Rodrigues, Tiffany K. Kaul, Jo-Hao Ho, Mark Lucanic, Kristopher Burkewitz, William B. Mair, Jason M. Held, Laura M. Bohn, Matthew S. Gill
Format: Article
Language:English
Published: Oxford University Press 2016-06-01
Series:G3: Genes, Genomes, Genetics
Subjects:
C. elegans
dauer
synthetic cannabinoids
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.026997

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