Distal renal tubular acidosis in sickle cell anemia
We report a rare case of two young male siblings with sickle cell anemia who presented with bilateral lower limb deformities, failure to thrive, polyuria, and polydipsia. On investigations, they were found to have normal anion gap metabolic acidosis, hypokalemia, and nephrocalcinosis were seen on ul...
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Wolters Kluwer Medknow Publications
2018-01-01
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Series: | Saudi Journal of Kidney Diseases and Transplantation |
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doaj-bd0b066751af4ede8891f758bcec18eb2020-11-25T00:57:33ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422018-01-012941000100410.4103/1319-2442.239637Distal renal tubular acidosis in sickle cell anemiaAnjali BharaniRani ManchandaRitesh Kumar SinghSwati PrashantWe report a rare case of two young male siblings with sickle cell anemia who presented with bilateral lower limb deformities, failure to thrive, polyuria, and polydipsia. On investigations, they were found to have normal anion gap metabolic acidosis, hypokalemia, and nephrocalcinosis were seen on ultrasonography of the kidneys. These reports were suggestive of distal renal tubular acidosis (dRTA). They were started on oral alkali replacement and potassium therapy with which clinical improvement was seen. Conventionally, renal tubular dysfunction is thought to occur infrequently in patients with sickle cell anemia. Hence, we report this rare association between sickle cell anemia and dRTA.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2018;volume=29;issue=4;spage=1000;epage=1004;aulast=Bharani |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anjali Bharani Rani Manchanda Ritesh Kumar Singh Swati Prashant |
spellingShingle |
Anjali Bharani Rani Manchanda Ritesh Kumar Singh Swati Prashant Distal renal tubular acidosis in sickle cell anemia Saudi Journal of Kidney Diseases and Transplantation |
author_facet |
Anjali Bharani Rani Manchanda Ritesh Kumar Singh Swati Prashant |
author_sort |
Anjali Bharani |
title |
Distal renal tubular acidosis in sickle cell anemia |
title_short |
Distal renal tubular acidosis in sickle cell anemia |
title_full |
Distal renal tubular acidosis in sickle cell anemia |
title_fullStr |
Distal renal tubular acidosis in sickle cell anemia |
title_full_unstemmed |
Distal renal tubular acidosis in sickle cell anemia |
title_sort |
distal renal tubular acidosis in sickle cell anemia |
publisher |
Wolters Kluwer Medknow Publications |
series |
Saudi Journal of Kidney Diseases and Transplantation |
issn |
1319-2442 |
publishDate |
2018-01-01 |
description |
We report a rare case of two young male siblings with sickle cell anemia who presented with bilateral lower limb deformities, failure to thrive, polyuria, and polydipsia. On investigations, they were found to have normal anion gap metabolic acidosis, hypokalemia, and nephrocalcinosis were seen on ultrasonography of the kidneys. These reports were suggestive of distal renal tubular acidosis (dRTA). They were started on oral alkali replacement and potassium therapy with which clinical improvement was seen. Conventionally, renal tubular dysfunction is thought to occur infrequently in patients with sickle cell anemia. Hence, we report this rare association between sickle cell anemia and dRTA. |
url |
http://www.sjkdt.org/article.asp?issn=1319-2442;year=2018;volume=29;issue=4;spage=1000;epage=1004;aulast=Bharani |
work_keys_str_mv |
AT anjalibharani distalrenaltubularacidosisinsicklecellanemia AT ranimanchanda distalrenaltubularacidosisinsicklecellanemia AT riteshkumarsingh distalrenaltubularacidosisinsicklecellanemia AT swatiprashant distalrenaltubularacidosisinsicklecellanemia |
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1725223572399456256 |