Splicing Enhancers at Intron–Exon Borders Participate in Acceptor Splice Sites Recognition

Splicing Enhancers at Intron–Exon Borders Participate in Acceptor Splice Sites Recognition

Acceptor splice site recognition (3′ splice site: 3′ss) is a fundamental step in precursor messenger RNA (pre-mRNA) splicing. Generally, the U2 small nuclear ribonucleoprotein (snRNP) auxiliary factor (U2AF) heterodimer recognizes the 3′ss, of which U2AF35 has a dual function: (i) It binds to the in...

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Bibliographic Details
Main Authors: Tatiana Kováčová, Přemysl Souček, Pavla Hujová, Tomáš Freiberger, Lucie Grodecká
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
pre-mRNA splicing
splicing enhancer
U2AF35
acceptor splice site recognition
SRSF1
Online Access:https://www.mdpi.com/1422-0067/21/18/6553

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