Estimating and comparing microbial diversity in the presence of sequencing errors
Estimating and comparing microbial diversity are statistically challenging due to limited sampling and possible sequencing errors for low-frequency counts, producing spurious singletons. The inflated singleton count seriously affects statistical analysis and inferences about microbial diversity. Pre...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2016-02-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/1634.pdf |