Exploratory RNA-seq analysis in healthy subjects reveals vulnerability to viral infections during a 12- month period of isolation and confinement

Exploratory RNA-seq analysis in healthy subjects reveals vulnerability to viral infections during a 12- month period of isolation and confinement

Exposure to stressful environments weakens immunity evidenced by a detectable reactivation of dormant viruses. The mechanism behind this observation remains unclear. We performed next generation sequencing from RNA extracted from blood samples of 8 male subjects collected before, during and after a...

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Bibliographic Details
Main Authors: Judith-Irina Buchheim, Jean-Noël Billaud, Matthias Feuerecker, Claudia Strewe, Carole Dangoisse, Andreas Osterman, Satish Mehta, Brian Crucian, Gustav Schelling, Alexander Choukér
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Stress
Isolation
Confinement
RNA-seq
Antiviral immunity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354620301101

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