Active and Repressive Chromatin-Associated Proteome after MPA Treatment and the Role of Midkine in Epithelial Monolayer Permeability

Active and Repressive Chromatin-Associated Proteome after MPA Treatment and the Role of Midkine in Epithelial Monolayer Permeability

Mycophenolic acid (MPA) is prescribed to maintain allografts in organ-transplanted patients. However, gastrointestinal (GI) complications, particularly diarrhea, are frequently observed as a side effect following MPA therapy. We recently reported that MPA altered the tight junction (TJ)-mediated bar...

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Bibliographic Details
Main Authors: Niamat Khan, Christof Lenz, Lutz Binder, Dasaradha Venkata Krishna Pantakani, Abdul R. Asif
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:International Journal of Molecular Sciences
Subjects:
mycophenolic acid
midkine
iMDK
tight junctions
Online Access:http://www.mdpi.com/1422-0067/17/4/597

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