(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine

New (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolut...

Full description

Bibliographic Details
Main Authors:	Vladimir A. Ogurtsov, Oleg A. Rakitin
Format:	Article
Language:	English
Published:	MDPI AG 2021-07-01
Series:	Molbank
Subjects:	2,3-dihydroindoles (indolines) (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine deprotection biological activity
Online Access:	https://www.mdpi.com/1422-8599/2021/3/M1248

id	doaj-bd32289ae1144a2d8801fbde679ef4ee
record_format	Article
spelling	doaj-bd32289ae1144a2d8801fbde679ef4ee2021-09-26T00:45:22ZengMDPI AGMolbank1422-85992021-07-012021M1248M124810.3390/M1248(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amineVladimir A. Ogurtsov0Oleg A. Rakitin1N. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, RussiaN. D. Zelinsky Institute of Organic Chemistry Russian Academy of Sciences, 47 Leninsky Prospekt, 119991 Moscow, RussiaNew (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolution mass-spectrometry, <sup>1</sup>H, <sup>13</sup>C NMR and IR spectroscopy and mass-spectrometry. The resulting compound is a convenient intermediate for various disubstituted 1-(indolin-5-yl)methanamines, which may be of interest as substances with useful pharmacological properties.https://www.mdpi.com/1422-8599/2021/3/M12482,3-dihydroindoles (indolines)(2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)aminedeprotectionbiological activity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Vladimir A. Ogurtsov Oleg A. Rakitin
spellingShingle	Vladimir A. Ogurtsov Oleg A. Rakitin (2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine Molbank 2,3-dihydroindoles (indolines) (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine deprotection biological activity
author_facet	Vladimir A. Ogurtsov Oleg A. Rakitin
author_sort	Vladimir A. Ogurtsov
title	(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine
title_short	(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine
title_full	(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine
title_fullStr	(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine
title_full_unstemmed	(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine
title_sort	(2,3-dihydro-1<i>h</i>-indol-5-ylmethyl)amine
publisher	MDPI AG
series	Molbank
issn	1422-8599
publishDate	2021-07-01
description	New (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine was synthesized from 2-((1-acetylindolin-5-yl)methyl)isoindoline-1,3-dione by simultaneous deprotection of phthalimide and acetyl groups. The structure of the newly synthesized compounds was established by elemental analysis, high resolution mass-spectrometry, <sup>1</sup>H, <sup>13</sup>C NMR and IR spectroscopy and mass-spectrometry. The resulting compound is a convenient intermediate for various disubstituted 1-(indolin-5-yl)methanamines, which may be of interest as substances with useful pharmacological properties.
topic	2,3-dihydroindoles (indolines) (2,3-dihydro-1<i>H</i>-indol-5-ylmethyl)amine deprotection biological activity
url	https://www.mdpi.com/1422-8599/2021/3/M1248
work_keys_str_mv	AT vladimiraogurtsov 23dihydro1ihiindol5ylmethylamine AT olegarakitin 23dihydro1ihiindol5ylmethylamine
_version_	1716869960175714304

(2,3-Dihydro-1<i>H</i>-indol-5-ylmethyl)amine

Similar Items