T follicular helper and T follicular regulatory cells have different TCR specificity
T follicular helper and regulatory cells are generated in the germinal centre; however, whether antigen specificity defines their differential functions is unclear. Here the authors show that T cells with distinct antigen specificity spectra are recruited to the germinal centre to establish these tw...
Main Authors: | Ana Raquel Maceiras, Silvia Cristina Paiva Almeida, Encarnita Mariotti-Ferrandiz, Wahiba Chaara, Fadi Jebbawi, Adrien Six, Shohei Hori, David Klatzmann, Jose Faro, Luis Graca |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-04-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms15067 |
Similar Items
-
Interleukin-1 in the Response of Follicular Helper and Follicular Regulatory T Cells
by: Paul-Gydéon Ritvo, et al.
Published: (2019-02-01) -
RepSeq Data Representativeness and Robustness Assessment by Shannon Entropy
by: Wahiba Chaara, et al.
Published: (2018-05-01) -
The Role of T Follicular Helper Cells and T Follicular Regulatory Cells in the Pathogenesis of Autoimmune Hemolytic Anemia
by: Yuhan Gao, et al.
Published: (2019-12-01) -
T Follicular Regulatory Cell Suppression of T Follicular Helper Cell Function Is Context-Dependent in vitro
by: Maria Lopez-Ocasio, et al.
Published: (2020-04-01) -
Imbalance of Circulatory T Follicular Helper and T Follicular Regulatory Cells in Patients with ANCA-Associated Vasculitis
by: Ying Xu, et al.
Published: (2019-01-01)