Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients

Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients

Abstract Background Mitochondrial dysfunction may represent a pathogenic factor in Huntington disease (HD). Physical exercise leads to enhanced mitochondrial function in healthy participants. However, data on effects of physical exercise on HD skeletal muscle remains scarce. We aimed at investigatin...

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Bibliographic Details
Main Authors: Sandro Manuel Mueller, Saskia Maria Gehrig, Jens A. Petersen, Sebastian Frese, Violeta Mihaylova, Maria Ligon-Auer, Natalia Khmara, Jean-Marc Nuoffer, André Schaller, Carsten Lundby, Marco Toigo, Hans H. Jung
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Mitochondrial respiration
Citrate synthase
Mitochondrial respiratory chain
Neuromuscular disease
Online Access:http://link.springer.com/article/10.1186/s13023-017-0740-z

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