Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.

Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.

Intracerebral microhemorrhages (CMHs) are small foci of hemorrhages in the cerebrum. Acute infections induced by some intracellular pathogens, including rickettsia, can result in CMHs. Annexin a2 (ANXA2) has been documented to play a functional role during intracellular bacterial adhesion. Here we r...

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Bibliographic Details
Main Authors: Zhengchen Su, Qing Chang, Aleksandra Drelich, Thomas Shelite, Barbara Judy, Yakun Liu, Jie Xiao, Changchen Zhou, Xi He, Yang Jin, Tais Saito, Shaojun Tang, Lynn Soong, Maki Wakamiya, Xiang Fang, Alexander Bukreyev, Thomas Ksiazek, William K Russell, Bin Gong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007960

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