Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments
There is a need for new, safer, and more effective agents to treat cancer. Cytostatics that have transition metals at their core have attracted renewed interest from scientists. Researchers are attempting to use chemotherapeutics, such as cisplatin, in combination therapy (i.e., in order to enhance...
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doaj-bd8151f1f6254a70b2cfd00a8bb3bb3a2021-08-06T15:26:06ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672021-07-01228271827110.3390/ijms22158271Platinum and Palladium Complexes as Promising Sources for Antitumor TreatmentsRobert Czarnomysy0Dominika Radomska1Olga Klaudia Szewczyk2Piotr Roszczenko3Krzysztof Bielawski4Department of Synthesis and Technology of Drugs, Medical University of Bialystok, Kilinskiego 1, 15-089 Bialystok, PolandDepartment of Synthesis and Technology of Drugs, Medical University of Bialystok, Kilinskiego 1, 15-089 Bialystok, PolandDepartment of Synthesis and Technology of Drugs, Medical University of Bialystok, Kilinskiego 1, 15-089 Bialystok, PolandDepartment of Synthesis and Technology of Drugs, Medical University of Bialystok, Kilinskiego 1, 15-089 Bialystok, PolandDepartment of Synthesis and Technology of Drugs, Medical University of Bialystok, Kilinskiego 1, 15-089 Bialystok, PolandThere is a need for new, safer, and more effective agents to treat cancer. Cytostatics that have transition metals at their core have attracted renewed interest from scientists. Researchers are attempting to use chemotherapeutics, such as cisplatin, in combination therapy (i.e., in order to enhance their effectiveness). Moreover, studies are being carried out to modify molecules, by developing them into multinuclear structures, linking different compounds to commonly used drugs, or encapsulating them in nanoparticles to improve pharmacokinetic parameters, and increase the selectivity of these drugs. Therefore, we attempted to organize recent drug findings that contain palladium and platinum atoms in their structures.https://www.mdpi.com/1422-0067/22/15/8271platinum complexespalladium complexesanticancer treatments |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Robert Czarnomysy Dominika Radomska Olga Klaudia Szewczyk Piotr Roszczenko Krzysztof Bielawski |
spellingShingle |
Robert Czarnomysy Dominika Radomska Olga Klaudia Szewczyk Piotr Roszczenko Krzysztof Bielawski Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments International Journal of Molecular Sciences platinum complexes palladium complexes anticancer treatments |
author_facet |
Robert Czarnomysy Dominika Radomska Olga Klaudia Szewczyk Piotr Roszczenko Krzysztof Bielawski |
author_sort |
Robert Czarnomysy |
title |
Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments |
title_short |
Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments |
title_full |
Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments |
title_fullStr |
Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments |
title_full_unstemmed |
Platinum and Palladium Complexes as Promising Sources for Antitumor Treatments |
title_sort |
platinum and palladium complexes as promising sources for antitumor treatments |
publisher |
MDPI AG |
series |
International Journal of Molecular Sciences |
issn |
1661-6596 1422-0067 |
publishDate |
2021-07-01 |
description |
There is a need for new, safer, and more effective agents to treat cancer. Cytostatics that have transition metals at their core have attracted renewed interest from scientists. Researchers are attempting to use chemotherapeutics, such as cisplatin, in combination therapy (i.e., in order to enhance their effectiveness). Moreover, studies are being carried out to modify molecules, by developing them into multinuclear structures, linking different compounds to commonly used drugs, or encapsulating them in nanoparticles to improve pharmacokinetic parameters, and increase the selectivity of these drugs. Therefore, we attempted to organize recent drug findings that contain palladium and platinum atoms in their structures. |
topic |
platinum complexes palladium complexes anticancer treatments |
url |
https://www.mdpi.com/1422-0067/22/15/8271 |
work_keys_str_mv |
AT robertczarnomysy platinumandpalladiumcomplexesaspromisingsourcesforantitumortreatments AT dominikaradomska platinumandpalladiumcomplexesaspromisingsourcesforantitumortreatments AT olgaklaudiaszewczyk platinumandpalladiumcomplexesaspromisingsourcesforantitumortreatments AT piotrroszczenko platinumandpalladiumcomplexesaspromisingsourcesforantitumortreatments AT krzysztofbielawski platinumandpalladiumcomplexesaspromisingsourcesforantitumortreatments |
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1721218196253442048 |