Successful Treatment of Metastatic Brain Tumor by CyberKnife: A Case Report

• Main Authors: Cheng-Ta Hsieh, Cheng-Fu Chang, Ming-Ying Liu, Li-Ping Chang, Dueng-Yuan Hueng, D. Chang Steven, Da-Tong Ju
• Format: Article
• Language: English
• Published: Wiley 2010-03-01
• Series: Kaohsiung Journal of Medical Sciences
• Subjects: brain metastases; CyberKnife; stereotactic radiosurgery
• Online Access: http://www.sciencedirect.com/science/article/pii/S1607551X10700218

Stereotactic radiosurgery plays an important role in management of metastatic brain tumors, especially when the tumor has recurred after treatment with previous whole brain radiotherapy. Most metastatic brain tumors less than 1 cm3 show a complete response after stereotactic radio-surgery. However, there are few reports of a dramatic change in the complete response of large metastatic brain tumors. Here, we report a case of adenocarcinoma of lung that had metastasized to the brain. Because the recurrence of the metastatic brain tumor measured approximately 3 cm in diameter, the tumor was previously treated with two prior craniotomies followed by whole brain radiation to the resection cavity. The tumor subsequently recurred and was treated with stereotactic radiosurgery (CyberKnife). A dramatic response was noted 3 months after radiosurgery with complete disappearance of the recurrent tumor.