Harnessing the immune response to target tumors [version 1; referees: 2 approved]

Development of “immune-based targeted therapy” in oncology has limited experience with signal pathway modulation. However, as we have become better versed in understanding immune function related to anticancer response, “hints” of specific targets associated with sensitivity and resistance have been...

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Bibliographic Details
Main Authors: Luisa Manning, John Nemunaitis
Format: Article
Language:English
Published: F1000 Research Ltd 2017-05-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-710/v1
Description
Summary:Development of “immune-based targeted therapy” in oncology has limited experience with signal pathway modulation. However, as we have become better versed in understanding immune function related to anticancer response, “hints” of specific targets associated with sensitivity and resistance have been identified with targeted immune therapy. This brief review summarizes the relationship of several targeted immune therapeutics and activity associated clinical responsiveness.
ISSN:2046-1402