The Early-Onset Myocardial Infarction Associated PHACTR1 Gene Regulates Skeletal and Cardiac Alpha-Actin Gene Expression.

The Early-Onset Myocardial Infarction Associated PHACTR1 Gene Regulates Skeletal and Cardiac Alpha-Actin Gene Expression.

The phosphatase and actin regulator 1 (PHACTR1) locus is a very commonly identified hit in genome-wide association studies investigating coronary artery disease and myocardial infarction (MI). However, the function of PHACTR1 in the heart is still unknown. We characterized the mechanisms regulating...

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Bibliographic Details
Main Authors: Annina Kelloniemi, Zoltan Szabo, Raisa Serpi, Juha Näpänkangas, Pauli Ohukainen, Olli Tenhunen, Leena Kaikkonen, Elina Koivisto, Zsolt Bagyura, Risto Kerkelä, Margret Leosdottir, Thomas Hedner, Olle Melander, Heikki Ruskoaho, Jaana Rysä
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4476650?pdf=render

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