Analysis of KRAS and NRAS mutations in Greek patients with metastatic Colorectal Cancer (mCRC) on the registry of the Gastro-intestinal Cancer Study Group (GIC-SG)

Analysis of KRAS and NRAS mutations in Greek patients with metastatic Colorectal Cancer (mCRC) on the registry of the Gastro-intestinal Cancer Study Group (GIC-SG)

Several studies show that mutational profiles could influence treatment decisions in patients with metastatic CRC (mCRC). KRAS mutational status was the first step in biomarkers development in the era of molecular targeted therapies. Recently, NRAS mutational status was identified as an independent...

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Bibliographic Details
Main Authors: Gouvas Nikolaos, Kalambaliki Telenia, Voutsina Alexandra, Saridaki Zenia, Tzardi Maria, Kalykaki Aristea, Sfakianaki Maria, Athanasiadis Athanasios, Xynos Evaghelos, Boukovinas Ioannis, Souglakos John
Format: Article
Language:English
Published: Sciendo 2019-07-01
Series:Forum of Clinical Oncology
Subjects:
kras-nras mutation
colorectal cancer
metastatic disease
Online Access:https://doi.org/10.2478/fco-2018-0005

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