Altered Methylation Profile of Lymphocytes Is Concordant with Perturbation of Lipids Metabolism and Inflammatory Response in Obesity

Obesity is associated with immunological perturbations that contribute to insulin resistance. Epigenetic mechanisms can control immune functions and have been linked to metabolic complications, although their contribution to insulin resistance still remains unclear. In this study, we investigated th...

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Bibliographic Details
Main Authors: Mette J. Jacobsen, Caroline M. Junker Mentzel, Ann Sofie Olesen, Thierry Huby, Claus B. Jørgensen, Romain Barrès, Merete Fredholm, David Simar
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2016/8539057