Molecular findings reveal possible resistance mechanisms in a patient with ALK-rearranged lung cancer: a case report and literature review

Molecular findings reveal possible resistance mechanisms in a patient with ALK-rearranged lung cancer: a case report and literature review

Background: Non-small-cell lung cancer (NSCLC) is recognised as a particularly heterogeneous disease, encompassing a wide spectrum of distinct molecular subtypes. With increased understanding of disease biology and mechanisms of progression, treatment of NSCLC has made remarkable progress in the pas...

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Bibliographic Details
Main Authors: George Pentheroudakis, Eirini Papadopoulou, George Nasioulas, Anastasia Kougioumtzi, Panagiotis Ntellas, Eleftherios Kampletsas
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:ESMO Open
Online Access:https://esmoopen.bmj.com/content/4/5/e000561.full

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