NTRK fusions in osteosarcoma are rare and non‐functional events
Abstract Neurotrophic tyrosine receptor kinase (NTRK) fusions are promising molecular targets that have been described in a broad range of malignant tumours. Fusions commonly lead to the expression of chimeric proteins with constitutive tyrosine kinase activation that drives tumorigenesis. Despite a...
Main Authors: | Baptiste Ameline, Karim H Saba, Michal Kovac, Linda Magnusson, Olaf Witt, Stefan Bielack, Michaela Nathrath, Karolin H Nord, Daniel Baumhoer |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-04-01
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Series: | The Journal of Pathology: Clinical Research |
Subjects: | |
Online Access: | https://doi.org/10.1002/cjp2.158 |
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