Brewer's Yeast Improves Blood Pressure in Type 2 Diabetes Mellitus

• Main Authors: Payam Hosseinzadeh, Abolghassem Djazayery, Seyed-Ali Mostafavi, Mohammad Hassan Javanbakht, Hoda Derakhshanian, Abbas Rahimiforoushani, Mahmoud Djalali
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2013-06-01
• Series: Iranian Journal of Public Health
• Subjects: Diabetes; Brewer's Yeast; Blood Pressure
• Online Access: http://ijph.tums.ac.ir/index.php/IJPH/article/view/3487/2162

Background: This study was conducted to investigate the effects of Brewer's yeast supplementation on serum lipoproteins and blood pressure in patients with Type 2 diabetes mellitus.Methods: In a randomized double blind clinical trial, 90 adults with type 2 diabetes mellitus were recruited, and divided randomly into 2 groups, trial group received brewer's yeast (1800 mg/day) and control group received placebo for 12 weeks. Weight, BMI, food consumption (based on 24 hour food recall), fasting serum lipoproteins (Cholesterol, Triglyceride, LDL-c, HDL-c), systolic and diastolic blood pressures were measured before and after the intervention. Data analyses were performed by Statistical Package for Social Sciences ver. 18.0, and the statistical tests included Independent t-test, Paired t-test, Kolmogorov-Smirnov and analysis of covariance. This trial was registered in Iranian Registry of Clinical Trials (IRCT), No.IRCT138807062513N1.Results: Eighty-four subjects (21 men and 63 women) aged 46.3±6.1 years completed the study. After 12 weeks supplementation, systolic and diastolic blood pressures were decreased in the group receiving brewer's yeast (4.1±1.5, P=0.007 and 5.7±0.6, P=0.001 respectively). No-significant changes in LDL-c, HDL-c, Triglyceride and Cholesterol were shown.Conclusion: Supplementation with Brewer's yeast besides the usual treatment of type 2 diabetes mellitus can reduce systolic and diastolic blood pressures in diabetic patients.