Quality assessment of DNA derived from up to 30 years old formalin fixed paraffin embedded (FFPE) tissue for PCR-based methylation analysis using SMART-MSP and MS-HRM

<p>Abstract</p> <p>Background</p> <p>The High Resolution Melting (HRM) technology has recently been introduced as a rapid and robust analysis tool for the detection of DNA methylation. The methylation status of multiple tumor suppressor genes may serve as biomarkers for...

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Bibliographic Details
Main Authors: Hager Henrik, Wiuf Carsten, Thestrup Britta B, Wojdacz Tomasz K, Kristensen Lasse S, Hansen Lise
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/453

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