Total neoadjuvant treatment in locally advanced rectal cancer

Locally advanced rectal cancer requires a multidisciplinary management, traditionally based on neo-adjuvant (chemo) radiotherapy, conservative surgery with total mesorectal excision and adjuvant chemotherapy. Despite effective in term of local control, this strategy is linked to a high risk of dista...

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Bibliographic Details
Main Authors: Francesca De Felice, Vincenzo Tombolini, Enrico Cortesi
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Translational Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S193652332100036X