The Effect of TGF-β on Treg Cells in Adverse Pregnancy Outcome upon Toxoplasma gondii Infection

The Effect of TGF-β on Treg Cells in Adverse Pregnancy Outcome upon Toxoplasma gondii Infection

Toxoplasma gondii (T. gondii) is a ubiquitous intracellular protozoan parasite that causes adverse pregnancy outcomes. Its infection downregulates the Treg cell population and TGF-β level, which may contribute to adverse pregnancy outcomes. TGF-β plays a critical role in Treg cell development, but w...

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Bibliographic Details
Main Authors: Mingdong Zhao, Haixia Zhang, Xianbing Liu, Yuzhu Jiang, Liqin Ren, Xuemei Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Microbiology
Subjects:
TGF-β
pSmad3
CTLA-4
PD-1
Treg cells
Toxoplasma gondii
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.00901/full

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