Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C.

Characterization of serum proteins associated with IL28B genotype among patients with chronic hepatitis C.

INTRODUCTION:Polymorphisms near the IL28B gene (e.g. rs12979860) encoding interferon λ3 have recently been associated with both spontaneous clearance and treatment response to pegIFN/RBV in chronic hepatitis C (CHC) patients. The molecular consequences of this genetic variation are unknown. To gain...

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Bibliographic Details
Main Authors: Derek D Cyr, Joseph E Lucas, J Will Thompson, Keyur Patel, Paul J Clark, Alexander Thompson, Hans L Tillmann, John G McHutchison, M Arthur Moseley, Jeanette J McCarthy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3130042?pdf=render

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