Inhibition of Ebola Virus by a Molecularly Engineered Banana Lectin.

Ebolaviruses cause an often rapidly fatal syndrome known as Ebola virus disease (EVD), with average case fatality rates of ~50%. There is no licensed vaccine or treatment for EVD, underscoring the urgent need to develop new anti-ebolavirus agents, especially in the face of an ongoing outbreak in the...

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Bibliographic Details
Main Authors: Evelyn M Covés-Datson, Julie Dyall, Lisa Evans DeWald, Steven R King, Derek Dube, Maureen Legendre, Elizabeth Nelson, Kelly C Drews, Robin Gross, Dawn M Gerhardt, Lisa Torzewski, Elena Postnikova, Janie Y Liang, Bhupal Ban, Jagathpala Shetty, Lisa E Hensley, Peter B Jahrling, Gene G Olinger, Judith M White, David M Markovitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007595