Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice

Integration of QTL and bioinformatic tools to identify candidate genes for triglycerides in mice

To identify genetic loci influencing lipid levels, we performed quantitative trait loci (QTL) analysis between inbred mouse strains MRL/MpJ and SM/J, measuring triglyceride levels at 8 weeks of age in F2 mice fed a chow diet. We identified one significant QTL on chromosome (Chr) 15 and three suggest...

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Bibliographic Details
Main Authors: Magalie S. Leduc, Rachael S. Hageman, Ricardo A. Verdugo, Shirng-Wern Tsaih, Kenneth Walsh, Gary A. Churchill, Beverly Paigen
Format: Article
Language:English
Published: Elsevier 2011-09-01
Series:Journal of Lipid Research
Subjects:
quantitative trait loci
gene expression
genetics
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520408582

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