Mir‐27a‐3p attenuates bronchiolitis obliterans in vivo via the regulation of dendritic cells’ maturation and the suppression of myofibroblasts’ differentiation

Mir‐27a‐3p attenuates bronchiolitis obliterans in vivo via the regulation of dendritic cells’ maturation and the suppression of myofibroblasts’ differentiation

Abstract Bronchiolitis obliterans (BO), is a chronic rejection phenotype characterized by chronic small airway fibrous obliteration, hinders the patients who suffer from lung transplanting for surviving longer. Cell‐based therapies using dendritic cells (DCs) and T regulatory cells (Tregs) have been...

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Bibliographic Details
Main Authors: Ming Dong, Xin Wang, Tong Li, Jing Wang, Yunwei Yang, Yi Liu, Yaqing Jing, Honglin Zhao, Jun Chen
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:Clinical and Translational Medicine
Subjects:
bronchiolitis obliterans
dendritic cells
lung transplantation
mir‐27a‐3p
Online Access:https://doi.org/10.1002/ctm2.140

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