Effect of Infusions of Non-Antibiotic Antibacterials Alone and in Combination with Cephradine on Milk Yield of Buffaloes Affected with Clinical Mastitis
The objective of the present study was to evaluate the effect of four non-antibiotic antibacterials alone or in combination with cephradine in buffaloes on milk yield of mastitis affected quarters. For this purpose, 270 clinically mastitic quarters were grouped in randomized pattern. Non-antibiotic...
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University of Agriculture, Faisalabad
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doaj-be7cd676c64f48e894866516eb4ea2502020-11-25T02:47:37ZengUniversity of Agriculture, FaisalabadPakistan Veterinary Journal0253-83182010-01-013013943Effect of Infusions of Non-Antibiotic Antibacterials Alone and in Combination with Cephradine on Milk Yield of Buffaloes Affected with Clinical MastitisM. Yousaf*, G. Muhammad1, M. Z. Khan2 and S. U. Rahman3The objective of the present study was to evaluate the effect of four non-antibiotic antibacterials alone or in combination with cephradine in buffaloes on milk yield of mastitis affected quarters. For this purpose, 270 clinically mastitic quarters were grouped in randomized pattern. Non-antibiotic antibacterials viz., 2.5% chlorpromazine (2 ml), 4% lidocaine (10 ml), 10% povidone-iodine (10 ml) and 99.5% dimethylsulphoxide (20 ml) alone and in combination with first generation cephalosporin (cephradine 500 mg) were instilled into clinically mastitic quarters daily for five days. The group administered cephradine alone served as control. Mean milk yield (L/quarter per day) was recorded before administration of treatment and over a period of 4 weeks post initiation of treatment. Among the 4 non-antibiotic antibacterials tested alone, chlorpromazine (CPZ) showed significantly higher (P<0.05) recuperative effect on the milk yield of clinically mastitic quarters of dairy buffaloes. However, dimethylsulphoxide (DMSO) when infused alone, further aggravated (P<0.05) the milk yield loss, indicating negative effect on milk yield improvement. Adjuncting cephradine with each of the non-antibiotic antibacterials, the lidocaine-cephradine group showed the highest effect (p<0.05) on net recovery of milk yield on day 28 post initiation of treatment. It was concluded that that CPZ can be used in clinical mastitis in buffaloes as a low cost alternative to expensive branded antibiotics. Further, the use of lidocaine with cepheradnie was superior to all other combination regimens in milk yield recovery.http://www.pvj.com.pk/pdf-files/30_1/39-43.pdfNon-antibiotic antibacterialsMilk yieldMastitisDairy buffalo |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
M. Yousaf*, G. Muhammad1, M. Z. Khan2 and S. U. Rahman3 |
spellingShingle |
M. Yousaf*, G. Muhammad1, M. Z. Khan2 and S. U. Rahman3 Effect of Infusions of Non-Antibiotic Antibacterials Alone and in Combination with Cephradine on Milk Yield of Buffaloes Affected with Clinical Mastitis Pakistan Veterinary Journal Non-antibiotic antibacterials Milk yield Mastitis Dairy buffalo |
author_facet |
M. Yousaf*, G. Muhammad1, M. Z. Khan2 and S. U. Rahman3 |
author_sort |
M. Yousaf*, G. Muhammad1, M. Z. Khan2 and S. U. Rahman3 |
title |
Effect of Infusions of Non-Antibiotic Antibacterials Alone and in Combination with Cephradine on Milk Yield of Buffaloes Affected with Clinical Mastitis |
title_short |
Effect of Infusions of Non-Antibiotic Antibacterials Alone and in Combination with Cephradine on Milk Yield of Buffaloes Affected with Clinical Mastitis |
title_full |
Effect of Infusions of Non-Antibiotic Antibacterials Alone and in Combination with Cephradine on Milk Yield of Buffaloes Affected with Clinical Mastitis |
title_fullStr |
Effect of Infusions of Non-Antibiotic Antibacterials Alone and in Combination with Cephradine on Milk Yield of Buffaloes Affected with Clinical Mastitis |
title_full_unstemmed |
Effect of Infusions of Non-Antibiotic Antibacterials Alone and in Combination with Cephradine on Milk Yield of Buffaloes Affected with Clinical Mastitis |
title_sort |
effect of infusions of non-antibiotic antibacterials alone and in combination with cephradine on milk yield of buffaloes affected with clinical mastitis |
publisher |
University of Agriculture, Faisalabad |
series |
Pakistan Veterinary Journal |
issn |
0253-8318 |
publishDate |
2010-01-01 |
description |
The objective of the present study was to evaluate the effect of four non-antibiotic antibacterials alone or in combination with cephradine in buffaloes on milk yield of mastitis affected quarters. For this purpose, 270 clinically mastitic quarters were grouped in randomized pattern. Non-antibiotic antibacterials viz., 2.5% chlorpromazine (2 ml), 4% lidocaine (10 ml), 10% povidone-iodine (10 ml) and 99.5% dimethylsulphoxide (20 ml) alone and in combination with first generation cephalosporin (cephradine 500 mg) were instilled into clinically mastitic quarters daily for five days. The group administered cephradine alone served as control. Mean milk yield (L/quarter per day) was recorded before administration of treatment and over a period of 4 weeks post initiation of treatment. Among the 4 non-antibiotic antibacterials tested alone, chlorpromazine (CPZ) showed significantly higher (P<0.05) recuperative effect on the milk yield of clinically mastitic quarters of dairy buffaloes. However, dimethylsulphoxide (DMSO) when infused alone, further aggravated (P<0.05) the milk yield loss, indicating negative effect on milk yield improvement. Adjuncting cephradine with each of the non-antibiotic antibacterials, the lidocaine-cephradine group showed the highest effect (p<0.05) on net recovery of milk yield on day 28 post initiation of treatment. It was concluded that that CPZ can be used in clinical mastitis in buffaloes as a low cost alternative to expensive branded antibiotics. Further, the use of lidocaine with cepheradnie was superior to all other combination regimens in milk yield recovery. |
topic |
Non-antibiotic antibacterials Milk yield Mastitis Dairy buffalo |
url |
http://www.pvj.com.pk/pdf-files/30_1/39-43.pdf |
work_keys_str_mv |
AT myousafgmuhammad1mzkhan2andsurahman3 effectofinfusionsofnonantibioticantibacterialsaloneandincombinationwithcephradineonmilkyieldofbuffaloesaffectedwithclinicalmastitis |
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