Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney
After acute kidney injury (AKI), surviving cells within the nephron proliferate and repair. We identify Sox9 as an acute epithelial stress response in renal regeneration. Translational profiling after AKI revealed a rapid upregulation of Sox9 within proximal tubule (PT) cells, the nephron cell type...
Main Authors: | Sanjeev Kumar, Jing Liu, Paul Pang, A. Michaela Krautzberger, Antoine Reginensi, Haruhiko Akiyama, Andreas Schedl, Benjamin D. Humphreys, Andrew P. McMahon |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2015-08-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715007949 |
Similar Items
-
Distinct Transcriptional Programs Underlie Sox9 Regulation of the Mammalian Chondrocyte
by: Shinsuke Ohba, et al.
Published: (2015-07-01) -
Identification of a Multipotent Self-Renewing Stromal Progenitor Population during Mammalian Kidney Organogenesis
by: Akio Kobayashi, et al.
Published: (2014-10-01) -
Cellular and molecular studies of DNA repair in mammalian cells
by: Jones, N. J.
Published: (1987) -
INJURED ARTICULAR CARTILAGE REPAIR
by: Ariana Barlič, et al.
Published: (2008-02-01) -
Ultrastructural evaluation of pathological and acutely injured mammalian corneas
by: Dooley, Erin P.
Published: (2012)