Expression of GITR Enhances Multiple Myeloma Cell Sensitivity to Bortezomib.
Recently tumor necrosis factor receptor super family member 18 (TNFRSF18, also called GITR) has been identified as a novel tumor suppressor gene in Multiple Myeloma (MM), undergoing aberrant DNA methylation-mediated gene expression silencing. Furthermore, the expression of GITR blocks canonical NF-κ...
Main Authors: | Yinghao Zhao, Kun Zhang, Guangquan Li, Xingyi Zhang, Donglei Shi |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4431824?pdf=render |
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