Molecular rheotaxis directs DNA migration and concentration against a pressure-driven flow

Implementing a nucleic acid preconcentration method can improve the sensitivity of microfluidic analysis systems. Here Friedrich et al. concentrate DNA by many orders of magnitude using pressure-driven flow, which could lead to a simple and practical microanalysis platform.

Bibliographic Details
Main Authors: Sarah M. Friedrich, Jeffrey M. Burke, Kelvin J. Liu, Cornelius F. Ivory, Tza-Huei Wang
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01214-y