Enantioseparation and Absolute Configuration Determination of Angular-Type Pyranocoumarins from Peucedani Radix Using Enzymatic Hydrolysis and Chiral HPLC-MS/MS Analysis

Enantioseparation and Absolute Configuration Determination of Angular-Type Pyranocoumarins from Peucedani Radix Using Enzymatic Hydrolysis and Chiral HPLC-MS/MS Analysis

Angular-type pyranocoumarins from Peucedani Radix (Chinese name: Qian-hu) have exhibited potential for use on treatment of cancer and pulmonary hypertension. Due to the existence of C-3′ and C-4′ chiral centers, compounds belonging to this chemical type commonly exist in enantiomers and/or diastereo...

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Bibliographic Details
Main Authors:	Yi-Tao Wang, Ru Yan, Ya-Ping Li, Yue-Lin Song, Qing-Wen Zhang
Format:	Article
Language:	English
Published:	MDPI AG 2012-04-01
Series:	Molecules
Subjects:	angular-type pyranocoumarins cis-khellactone absolute configuration enzymatic hydrolysis chiral LC-MS/MS
Online Access:	http://www.mdpi.com/1420-3049/17/4/4236/

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