Proteomic analysis of bone marrow-derived mesenchymal stem cell extracellular vesicles from healthy donors: implications for proliferation, angiogenesis, Wnt signaling, and the basement membrane

Abstract Background Bone marrow-derived mesenchymal stem cells (BM-MSCs) have shown therapeutic potential in various in vitro and in vivo studies in cutaneous wound healing. Furthermore, there are ubiquitous studies highlighting the pro-regenerative effects of BM-MSC extracellular vesicles (BM-MSC E...

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Bibliographic Details
Main Authors: Jeffrey D. McBride, Luis Rodriguez-Menocal, Wellington Guzman, Aisha Khan, Ciara Myer, Xiaochen Liu, Sanjoy K. Bhattacharya, Evangelos V. Badiavas
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-021-02405-7