Anaplasma phagocytophilum Activates NF-κB Signaling via Redundant Pathways

Anaplasma phagocytophilum subverts neutrophil function permitting intracellular survival, propagation and transmission. Sustained pro-inflammatory response, recruitment of new host cells for population expansion, and delayed apoptosis are associated with prolonged nuclear presence of NF-κB. We inves...

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Bibliographic Details
Main Authors: J. Stephen Dumler, Marguerite Lichay, Wan-Hsin Chen, Kristen E. Rennoll-Bankert, Jin-ho Park
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2020.558283/full